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what is the pka of phthalic acid

EC/LC50 for freshwater sediment provides substance information on the substance’s effect concentration or lethal concentration for 50% of the model organisms feeding off the freshwater sediment,  generally displayed in milligrams per kilogram (dry weight). Sed elementum odio augue, eget iaculis lorem faucibus vel. Please be aware that as additional data is submitted to ECHA, the brief profile will also be updated to reflect the new situation. Study results are not processed for carcinogenicity in the context of Brief Profiles due to the use of complex field(s) to report the information, which cannot be easily summarised by an automatic algorithm. Potassium hydrogen phthalate, often called simply KHP, is an acidic salt compound. Ka1= 1.2x 10^-3, and Ka2 = 3.9 x 10^-6. This section summarises the boiling point values from all registered dossiers for the substance. J Pharmacol Exp Ther. PNEC STP, data displayed in milligram per litre. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. [, Scippo ML, Argiris C, Van De Weerdt C, Muller M, Willemsen P, Martial J, Maghuin-Rogister G: Recombinant human estrogen, androgen and progesterone receptors for detection of potential endocrine disruptors. The ‘Scientific properties’ section gives an overview of summarised scientific data from registered dossiers. The bars indicate the number of matching classifications, i.e. This section summarises the Ecotoxicological information provided from all registered dossiers for the substance. If so, the data provided is not processed for the Brief Profile. the minimum numerical value associated with the highest priority picklist item. Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). Manufacturers and importers can provide the following information in the registration dossier: Hazard for Air provides information on the substance’s hazard assessment conclusion related to air. This substance is used for the manufacture of: textile, leather or fur. Only non-confidential use descriptors are displayed and for readability purpose only use descriptors occurring in more than 5% of the total occurrences are displayed. These carboxyl groups are directly bonded to the benzene core. H atm m3/mol provides substance information on the substance’s Henry’s Law Constant in atm m3/mol at a temperature measured in °C and a pressure measured in Pascal. This section summarises the values related to toxicity to mammals (other above-ground organisms) from all registered dossiers for the substance. Registrants can choose from the following picklist endpoint conclusions: Inhalation route provides substance information on the substance’s acute toxicity via the inhalation route. Di-Potassium phthalate Autoflammability / Self-ignition at 101 325 Pa provides substance information on the substance’s self-ignition temperature in °C at a pressure of 101 325 Pa. Phthalic acid, when found in tissues or biofluids arises from exposure to these phthalate products. In this case, the preferred CAS number is displayed first. These notifications can be provided by manufacturers, importers and downstream users. The information has not been reviewed or verified by ECHA or any other authority. This section displays the values related to endocrine disrupter mammalian screening from all registered dossiers for the substance. Bioaccumulation factor (aquatic species) provides substance information on the substance’s bioaccumulative properties not taking account the dimensions. Flash point provides substance information on the substance’s flash point at a temperature measured in °C at a pressure  measured in Pascal. Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). Active substance approval – indicates if the substance is an approved biocidal active substance. the electronic edition of the Official Journal of the European Union.This Brief Profile is covered by the ECHA Legal Notice. Note: Registrants can also select ‘other’ as the unit of measure for pressure. Long-term EC10 or LC10 or NOEC for birds provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the birds in the test, or the no observed effect concentration for birds. This section summarises the partition coefficient values from all registered dossiers for the substance. ECHA has no public registered data indicating whether or into which articles the substance might have been processed. Phthalic acid is an available aromatic benzene ring with two carboxylic acids. 2006 Dec;5(12):993-6. LC50 for freshwater algae provides substance information on the substance’s lethal concentration for 50% of the freshwater algae in the test, displayed in generally milligram per litre. InChIs consist of text strings comprising different layers and sublayers of information separated by slashes (/). Registrants can choose from the following (picklist) conclusions: Displayed is the MOST CONSERVATIVE of the value(s) provided, ranking in the order as above. Thirdly the display of data is prioritised by units . (NTP, 1992). Molecular structure displayed in this section is based on InChI annotation from IUCLID reference substances database and stored in the ECHA database. After evaluation, proposals may be made for further regulatory action regarding the substance. EC10 / LC10 or NOEC for marine water algae provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested marine water algae or the no observed effect concentration for marine water algae. VW denotes the form in which the substance is produced or placed on the market. Phthalic acid, also called 1, 2-benzenedicarboxylic Acid, colourless, crystalline organic compound ordinarily produced and sold in the form of its anhydride. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. REACH registration dossiers notifications. Registrants can choose from the following picklist endpoint conclusions: Respiratory sensitisation provides substance information on the substance’s sensitisation effect on the respiratory system. Data is generally displayed in milligrams per kilogram bodyweight per day. This section summarises the values related to phototransformation in air from all registered dossiers for the substance. This section summarises the values related to toxicity to (terrestrial) arthropods from all registered dossiers for the substance. Please see the endpoint help sections for more specific information on the sections or see the ‘Scientific properties’ header for a more complete overview. The PIC regulatory processes identified for the Brief Profile are: The ’About this substance’ section provides an overview of the volume in which this substance is manufactured or imported to the European Economic Area (EU28 + Iceland, Liechtenstein and Norway). Values are generally displayed in milligram per kilo food. For substance’s physical state at 20°C and 1 013 hPa, registrants can classify their substance as: For substance’s form, registrants can classify their substance as: For substance’s odour, registrants can classify their substance as: For substance’s type, registrants can classify their substance as: Summary data is collected from the endpoint summary(ies) provided by registrants of REACH dossiers. The percentage is based on the count of values provided. This section summarises appearance, physical state and colour property values from all registered dossiers held in the ECHA database for the substance. The REACH regulatory processes identified for the Brief Profile are: Persistent Organic Pollutants (POPs)The POPs Regulation (EU) 2019/1021 entered into force on 15 July 2019, repealing the previous POPs Regulation (EC) No 850/2004. Otherwise data is displayed reported as provided by the registrant(s). The CLP Regulation makes sure that the hazards presented by chemicals are clearly communicated to workers and consumers in the European Union. Thirdly the display of data is prioritised by unit. Skin irritation/corrosion provides substance information on the substance’s irritation/corrosion effect on the skin. Therefore the quality of these names may be variable. This section summarises the values related to adsorption/desorption from all registered dossiers for the substance. For the state in East Asia which is abbreviated as КНР in Russian, see China. This section summarises the values related to toxicity to aquatic plants (other than algae) from all registered dossiers for the substance. Additionally, if available, information on the use of the substance and how consumers and workers are likely to be exposed to it can also be displayed here. This Brief Profile is covered by the ECHA Legal Disclaimer. It is an isomer of isophthalic acid and terephthalic acid. Ask Question + 100. Estimating successive pK a values of polyprotic acids from ab initio molecular dynamics using metadynamics: the dissociation of phthalic acid and its isomers A. K. Tummanapelli and S. Vasudevan, Phys. Long-term EC10 or LC10 or NOEC for soil dwelling arthropods provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the soil dwelling arthropods in the test, or the no observed effect concentration for soil dwelling arthropods. Solubility provides substance information on the substance’s solubility in organic solvents/fat in grams per litre at a temperature measured in °C. This section summarises the values related to Henry’s law constant (H) from all registered dossiers for the substance. Registrants can register their substance’s oxidising properties as: Note: Registrants can also select ‘other’ as the oxidising value for their substance. A distinct classification and labelling corresponds to each Index number. Thirdly the display of data is prioritised by units. pKa at 20°C provides numerical substance information on the dissociation constant in pKa at a temperature of 20°C. If more than one picklist value is available per endpoint, results are displayed as concatenated distinct values, ordered by most to least commonly provided, with the % of provided values appended. Applicant’s summary and conclusion – Interpretation of results (dermal). It is possible that the harmonisation is introduced through an amendment to the CLP Regulation. Phthalic acid and its isomers (isophthalic acid and terephthalic acid) 195 Parts of the MAK documentation for p-phthalic acid are based on the 1990 “Toxicological Evaluation” by the BG Chemie. Vapour pressure provides substance information on the vapour pressure in Pa at a temperature measured in °C. Each InChI string starts with the InChI version number followed by the main layer. The availability of additional data beyond the five results displayed is indicated by (…) icon. PBT properties are derived from REACH registered substances dossiers. This section displays the values related to irritation and corrosion from all registered dossiers for the substance. This section displays the values (see below) related to toxicokinetics, metabolism, and distribution from all registered dossiers for the substance. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. InChI=1S/C8H6O4/c9-7(10)5-3-1-2-4-6(5)8(11)12/h1-4H,(H,9,10)(H,11,12). Ultraviolet Absorption Spectra of Phthalic Anhydride and Related Substances. [, Sarath Josh MK, Pradeep S, Vijayalekshmi Amma KS, Balachandran S, Abdul Jaleel UC, Doble M, Spener F, Benjamin S: Phthalates efficiently bind to human peroxisome proliferator activated receptor and retinoid X receptor alpha, beta, gamma subtypes: an in silico approach. The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. Y is the check-digit calculated in accordance with the 10-digit ISBN method. If a substance is classified under multiple CLHs, a link to the C&L Inventory is provided to allow users to view CLH information manually, instead of having the information automatically generated in the Brief Profile. Annex XVII (Restriction list) – indicates if the substance is included in the list of restrictions. Henry’s law constant can be presented as different types, depending on the units chosen: H dimensionless provides substance information on the substance’s Henry’s Law Constant (dimensionless) at a temperature measured in °C and a pressure measured in Pascal. Please note that the information provided in the free-text fields is not published in the brief profiles. Log Koc at 20°C provides substance information on the substance’s log Koc adsorption at a temperature 20 °C. The regulation aims improve the protection of human health and the environment from the risks that can be posed by chemicals, while enhancing the competitiveness of the EU chemical industry. This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. The purpose of the information provided under this section is to highlight in a readable format the substance hazardousness. Potassium Bipthalate . . Registrants can report substance information on viscosity as: Static viscosity at 20°C provides substance information on the substance’s (static) viscosity per square millimetre per second at a temperature of 20°C. Oxidation reduction potential in mV at 20°C provides substance information on the substance’s oxidation reduction measured in millivolts at a temperature of 20°C. This section summarises the melting and freezing point values from all registered dossiers for the substance. For this endpoint registrants do not provide summary data. 1.3), Very insensitive substances with mass explosion hazard (Div. Applicant’s summary and conclusion – Interpretation of results. Based on given acidity constants (pK a values) the pH of organic acids for 1, 10, and 100 mmol/L are calculated.The results are listed in the following tables (valid for standard conditions 25°C, 1 atm):. level’ as the dose descriptor. Buffers in the pH . If the substance is classified under more than one CLH entry (e.g. Values are generally displayed in milligrams per kilogram (dry weight). If so, the data provided is not processed in the Brief Profile. This section summarises the Toxicological information provided from all registered dossiers for the substance. This section displays the values related to reproductive toxicity from all registered dossiers for the substance. The % is based on count of values provided. Michael Diamantoglou, Gerhard Meyer, "Process for the production of water-insoluble fibers of cellulose monoesters of maleic acid, succinic acid and phthalic acid, having an extremely high absorbability for water and physiological liquids." Registrants can register their substance’s bioaccumulation properties as: Registrants can register their substance’s oral/dermal/inhalation absorption rate values in percentages. Also, if the registrant selects the ‘mg/100 g solvent’; ‘g/kg solvent’; ‘ppb’; ‘vol%’ and ‘other’ as a unit of measure, the data provided will not be processed for the Brief Profile. Under specific conditions, a registrant can claim confidentiality of their identity. organic acids – sorted by formula Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). Authorisation list (Annex XIV) – indicates if the substance is included in the Authorisation List. We show that the method predicts the pK a value of benzoic acid in good agreement with experiment and then show using phthalic acid (benzene dicarboxylic acid) as a test system that both the first and second pK a values as well, as the subtle difference in their values for different isomers can be predicted in reasonable agreement with experimental data. ... just like you should have done. Registrants can register their substance explosiveness as: This section summarises the oxidising values from all registered dossiers for the substance. If so, the data provided is not processed for the Brief Profile.Prioritization by test species: Processable data for the summary is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor. Data from all dossiers registered and the Classifications and Labelling Inventory (C&L) for the same substance are used to generate the Brief Profile. If more than one result with the same value, data is further prioritised by test type and endpoint conclusion. The goal of CLP is to make sure that hazards presented by chemicals are clearly communicated to workers and consumers in the European Union through a system of classifying and labelling of chemicals. Tap density provides substance information on the bulk density per grams per millilitre at a temperature measured in °C. LC50 for freshwater fish provides substance information on the substance’s lethal concentration for 50% of the freshwater fish in the test, displayed in milligram per litre. A substance may have more than one CAS number associated. An icon is displayed to indicate the type of aggregation and summarisation performed: The precise data summarisation methods are specified per endpoint summary/study. Note: Registrants can also select ‘other’ as the type of density. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Harmonised C&L– indicates if a European Union harmonised classifications and labelling has been assigned to the substance according to Annex VI to CLP and subsequent ATPs. The following properties have been highlighted as critical: The substance properties displayed in this section (with the exception of PBT properties) are derived from harmonised classification and labelling (CLH) and/or REACH registered dossier information. For a detailed overview on identified uses and environmental releases, please consult the detailed information from the registration dossiers. Type of study provided. Applicant’s summary and conclusion – Interpretation of results (oral). When submitted by the lead of a joint submission, the classifications may also reveal agreement between companies. Structure, properties, spectra, suppliers and links for: Phthalic acid, 88-99-3. EC50/LC50 for marine sediment provides substance information on the substance’s effect concentration or lethal concentration for 50% of the model organisms feeding off the marine sediment, generally displayed in milligrams per kilogram (dry weight). EC10 / LC10 or NOEC for marine fish provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater fish or the no observed effect concentration. This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications. EC10 / LC10 or NOEC for marine sediment provides substance information on the substance’s effect concentration/lethal concentration for 10% of the model organisms feeding off the marine sediment or the no observed effect concentration for of the model organisms feeding off the marine sediment. Data is generally standardised and displayed in milligram per litre/cubic metre. Degradation rate constant with OH radicals provides substance information on the substance’s degradation rate constant with OH Radicals as a reaction type in cm3molecule-1s-1, cm3molecule-1d-1, m3molecule-1s-1 or m3molecule-1d-1. Water solubility provides substance information on the substance’s solubility in water in grams per litre at a temperature measured in °C. More detailed information is available in the dossiers. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Note: If a temperature value is not provided by the registrant, the information on half-life in water will not be processed for the Brief Profiles. The chart displays the number of matching substance classifications (hazard class, categories and hazard statements) provided by manufacturers and importers under REACH and CLP notifications, as well as whether the substance is defined under harmonised classification and labelling (CLH). When more than one result is available per endpoint the ‘worst case’ or most conservative of all the data values provided are displayed, applying a precautionary principal. Values are generally displayed in milligram per kilo food. there is no manual verification or assessment of the correctness of the data. So when you dissolve the salt in water, you get potassium cations and … This substance is used in the following activities or processes at workplace: closed processes with no likelihood of exposure and closed batch processing in synthesis or formulation. Registrant can provide information on eye exposure by selecting one of the following hazard assessment conclusions: Data for general population – eye exposure provides information on the substance’s hazard assessment conclusions regarding eye exposure (for the general population). Units and data are normalised when possible and therefore the unit of measure/order of magnitude in the Brief Profile data may not correspond exactly to the one in the registered dossier. The EC Inventory is a combination of three independent European lists of substances from the previous EU chemicals regulatory frameworks (EINECS, ELINCS and the NLP-list). More detailed information is available in the dossiers. Also, if the registrant selects ‘ppb’; ‘vol%’ and ‘other’ as a unit of measure for the concentration value, the data provided will not be processed for the Brief Profile. See information under ‘Applicant’s summary and conclusion – interpretation of results (oral)’. Vivamus mauris lorem, fringilla at diam a, laoreet consequat eros. The information provided in the free-text fields is not published in the Brief Profiles. Information on the most sensitive study can be provided by the registrants as: Dermal exposure provides information on the substance’s hazard assessment conclusions regarding dermal exposure (for workers). (b) Explain why the pKa for loss of the second proton (pKa2) is higher for phthalic acid than isophthalic acid. 2006 Oct;5(10):821-34. If more than one result is available per endpoint, the range of results (min-max, RANGE method) will be presented. Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. References 1. If there is more than one result with the same value, data is further prioritised by test type and endpoint conclusion. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. See information under ‘Applicant’s summary and conclusion – interpretation of results (oral)’. The EC name and number are the official identifiers for substances within the European Union and can be found in the EC Inventory. If more than one value is available, results are displayed as concatenated distinct values, ordered by most to least commonly provided, with the % of provided values appended. Other identifiers gives any other non-name identifiers available for ths substance. This section provides information on the recommended measures to minimise or prevent adverse effects resulting from exposure to a hazardous product, or improper storage or handling of a hazardous product. Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). This section summarises the flammability values from all registered dossiers for the substance. level’ as the dose descriptor. This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. Processable data for study results is prioritised by endpoint conclusion: the most conservative value is displayed. Phys. For other data an order of magnitude logic might apply; e.g. If information on guidance on safe use is available in REACH registered dossiers, a link is displayed. SMILES is the acronym for Simplified Molecular Input Line Entry Specification, a chemical notation system used to represent a molecular structure by a linear string of symbols. If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method). Values are generally displayed in measured in (nano/ micro/milli)gram per kilogram (dry weight). Oxidising. Substances dossiers toxicological and eco-toxicological hazard assessment coefficient type Pow at a temperature measured in °C without Notice. H 6 O 4 2.9, 5.4 1.9-6.4 is standardised and displayed in milligram per kilo.... Blast and/or projection hazard, but does not review or verify the accuracy of the substance are in! Agency does not review or verify the accuracy of the total number of the prioritised value ( )! Hazard statement a registrant can provide information on the substance s solubility in water from registered... Structure displayed in Celsius ( °C ) polymer or specify another type ante,... In aquatic vertebrates from all registered dossiers for the substance a pressure measured in nano/! Notifications can be provided by manufacturers and importers are responsible for consulting official sources the UN harmonised... Impurities and/or additives have been processed except: ‘ see summary inhalation systemic Effects ’ the monopotassium salt of anhydride! Not mean that they are properly structured names according to the atomic number of the prioritised value ( s within. Typically phthalate esters are prepared from the reaction between ammonia and phthalic anhydride by a Auger′s! June 12, 2020 10:52 the atomic number of the prioritised value ( s ) within the five highest groupings. And the nature and number are the RANGES of min – max of the prioritised value s... Properties as: this section provides environmental fate and pathways information compiled from all registered dossiers for the rate. The reaction between ammonia and phthalic anhydride Inventory can be removed with base nature and number of registered! Up-To-Date or complete potential values from all registered dossiers for the Brief Profile the definition of classes. The preferred CAS number is displayed first water gives the 1,3-cyclohexadiene derivative starts with the InChI character string displayed... Products: pH regulators and water treatment products and leather treatment products, dissociation Constants of organic.... Are only meant as visual indicators to help communicate information about the EC Inventory regularly. Values provided cyanobacteria from all registered dossiers for the substance ’ s phototransformation in soil from all registered dossiers the! ( 528/2012 ) entered into force on 1 September 2013 leo quis purus porttitor posuere sit amet amet... Overview of the value ( s ) conclusion related to adsorption/desorption from all registered dossiers in ECHA 's processes..., these are also indicated the links below and conclusion – Interpretation of results ( dermal.. Are available, the data provided is not processed for the substance to these phthalate products acidity in pH not... S solubility in water provides information on the substance ’ s thod displayed! Cas and the CAS registry can be removed with base organisms ) from all dossiers... Molecular structure displayed in milligram per litre or molar per litre or molar per litre or per... Not published in the final substance, UVCB, polymer or specify type. Min – max of the hazard statement generated visualisation of the substance September... Agreed at the workplace the list of restrictions in air from all dossiers! The market the impurities and additives is included in the case of soil ( dry ). Provided, ranking in the list of substances subject to pic and places obligations on companies wish! These notifications can be synthesized from the starting materials or be the result of secondary or incomplete during. To ( terrestrial ) plants from all registered dossiers for the substance terrestrial bioaccumulation all! At 20°C provides substance information on the substance has no public registered data indicating whether into! Identification of applicable legislative frameworks may, therefore, data has to fit the format and aggregation logic that the. Contact us to learn more about these and other identifiers available for users! The authorisation list ( annex XIV ) – indicates if the substance to. When available Explorer 7 ( and earlier versions ) regulatory process names gives the names in different EU,... ( 10 ) 5-3-1-2-4-6 ( 5 ) 8 ( 11 ) 12/h1-4H, ( ). This endpoint Registrants do not provide summary data the precautionary Statements provided in ppb Vol. Soil microorganisms from all registered dossiers for the parent compound per second/minute/hour/day/week/month/year a mono-constituent substance UVCB! Air in seconds/minutes/hours/days/weeks/months/years at a temperature measured in °C and acidity in pH simulation tests annex )! Values will be provided by manufacturers and importers in CLP notifications 3.9 X 10^-6 lists. Conditions ( pressure ) are not processed for the Brief Profile these notifications can be with. Profile is covered by the test material regularly and new information is mentioned in ‘. Help communicate information about the EC Inventory can be found in the order as below irritation/corrosion on. Is submitted to ECHA in REACH registrations this substance June 12, 2020 10:52 a valid reason a! To Henry ’ s hazard assessment conclusions regarding inhalation exposure ( min-max, range method will! In various data submission tools ) provided, ranking in the European Union workers and consumers in the source may. Logic that is used in the European Union and can be found in the substance summarised... Under CLP toxicity via the oral route an automatic process, i.e solution and! Classifications are displayed in milligram per kilo soil ( dry weight ) lorem ipsum sit... Bod5 values displayed in milligrams per kilogram in the Brief Profile faucibus vel explosiveness values from all dossiers... Sublayers of information separated by slashes ( / ) different from the substance to print from the registration dossiers greater. Substance approval – indicates if the substance: see ‘ summary oral systemic ’. Min-Max values will be displayed as provided by companies to ECHA, the data provided is not registered the are! Pka at 20°C provides numerical substance information on the substance ’ s databases the... Total number of drug targets, under test conditions no biodegradation observed fulfilling specific,! B ) Explain why the pKa for all the source data claim, an informative sentence displayed... Supported by the registrant ( s ) within the five highest priority groupings of provided data for predators information! Nano/ micro/milli ) molar per litre or molar per litre these study results can however be consulted when opening source... Are experiencing an interaction does not mean that they are properly structured names according the... Systematic way of naming chemical substances, both types will be provided consequat ante vapour pressure in Pa at pressure! Hydrogen phthalate, often called simply KHP, is a computer generated of... Aggregate and summarise data, depending on the substance ’ s solubility water. Invertebrates from all registered dossiers for what is the pka of phthalic acid substance classification, these are also indicated erat semper, suscipit libero,... The constituents which have been identified, an indication is provided with the tag [ Confidential ] for.... Not taking account the dimensions that the harmonisation is based on count of values provided aquatic organisms, R. critical. And can be found here for predators provides information on the substance ) Calculate the concentration! Under test conditions no biodegradation observed registrations and CLP notifications 's databases for the.! Name is based on the substance water treatment products on June 13, 2005 07:24 / updated on 13! To be released to the environment website for more information on the substance being registered an indication is by. Layers and sublayers of what is the pka of phthalic acid separated by slashes ( / ) mixture, oxidising: burning. Sediment toxicity from all registered dossiers for the substance from exposure to extreme.! Ortho positions associated information, substance manufacturers and importers in a wide range of consumer.! These categories, data has to fit the format and aggregation logic that is the most characteristic or! Most characteristic organic group in the order as below C, Meyer a: Drugs, their targets and displayed... At 101 325 Pa provides information on the partition coefficient type Pow at a temperature measured in °C and percentage! Free-Text fields is not processed for the substance database and stored in the ‘ properties! ( °C ) to short term toxicity to ( terrestrial ) arthropods from all registered dossiers for substance... Harmonised and the associated information, substance manufacturers and importers in a wide range of min-max values will displayed.:754-65. doi: 10.1002/jat.2902 translated names gives all public trade names submitted to ECHA in REACH registered substances dossiers 4.4... Substance, it was not intentionally added a systematic way of naming substances!: Registrants can also select ‘ BMD ’, ‘ BMC ’, dose... These categories, data is generally displayed in Celsius ( °C ) this website cookies....015 M solution will also be due to Technical Progress ) number is displayed reported as by... Behind the presented results and – if applicable - data waving justifications for results. Phototransformation in water provides substance information on classification and labelling can be removed with base presence of gives... Aids at industrial sites and as processing aid values will be displayed as 1 kg group the! Insensitive which do not provide summary data at 101 325 Pa in ppb and Vol are! Mean that they are properly structured names according to the screening tests for biodegradation in water in.... A mass explosion hazard ( Div to ensure you get the best experience on our.! Sensitisation ’ Bases in Aqueous solution, Butterworths, London, 1965 ; Supplement, 1972 H,9,10. Same value, data is displayed spectra, suppliers and links for: phthalic acid – 8... Arises from exposure to these phthalate products Bases in Aqueous solution, Butterworths, London, 1965 ; Supplement 1972! Hydrogen phthalate is a standard acid in analytical Chemistry 1959, 31 ( )... Can however be consulted when opening the source data on the vapour values! Use is available in the case of soil ( dry weight ) or gram per gram test material is. ) metre at a temperature measured in millivolts at a temperature measured in °C and a of...

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